top of page
Nanoscale Adhesion and Migration
We are interested in the integration of materials and science with cell biology at the nanoscale since it allows the study of cell adhesion signalling at a single cell and collective cell level. In particular, we have developed a micro-nanopatterning setup to control integrin clustering in migrating cells in 1D and 2D environments with different adhesive peptides using nanotechnology and photopatterning.
MOLECULAR REGULATION OF ADHESION AND MIGRATION: About
A Wound Healing Approach
Wound Healing and PIV
Collective Cell Migration
MOLECULAR REGULATION OF ADHESION AND MIGRATION: Services
We are interested in developing a 3D-1D tumoral microenvironment system to study the relevant factor between the mechanical property of 3D milieus and the pathology of cancer progression. In order to further mimic the presence of aligned collagen fibers in primary tumors, which allow cancer cells to migrate out of malignant tissues, a 1D micropatterned surface is established to resemble the process of invasion into lymph or blood vessels. In this project, we focus on studying how solid stress from a 3D milieus plays a role in cancer cell motility and mechanics behavior.
- I Chen
MOLECULAR REGULATION OF ADHESION AND MIGRATION: Video
MOLECULAR REGULATION OF ADHESION AND MIGRATION: Pro Gallery
bottom of page